|Name of the Project
||National Hospital Based Rotavirus Network Project
||Dr. Sanjay Mehendale (Coordinator)
||Dr. C.P.Girish Kumar, Dr. S. Venkatasubramanian
||Rotavirus surveillance network group
Coordinating center- NIE
Referral centers- NIV, CMC, NICED, AIIMS
Regional centers- RMRCs at Port Blair,Jabalpur, Dibrugarh, Belgaum, Bhuvaneshwar &
RMIMS PatnaPeripheral centers-
32 hospital sites across the country
|Funding Agency / Sponsor
||NIE Budget : ~2.3 crores / 4 years, Overall Budget-: ~28 crores / 4 years
||4 years (2012-2016)
- To establish a national hospital based surveillance to examine long term trends and pattern of diarrhea attributable to rotavirus among children < 5 years of age seen at in-patient facilities
- To determine the age, seasonal distribution and outcomes of rotavirus-associated disease among the population under surveillance, including monitoring trends over time.
- To investigate the molecular epidemiology of rotavirus in India by typing the G and P type and characterization of untypable strains by sequencing.
- To estimate the economic burden of rotavirus gastroenteritis seen at hospitals by standardized costing studies.
||All children less than 5
years of age presenting with diarrhoea will be enrolled after obtaining
informed and written consent from the parent/guardian. Clinical information and
a stool specimen will be obtained from each enrolled child. The stool sample
will be tested for the presence of rotavirus by ELISA. Rotavirus positive stool
specimens will be further characterized to determine the G and P types of
strains using a variety of molecular methods, including muliplex RT-PCR and
specific priming and PCR for specific genotypes. Quality assurance excercises
will be conducted periodically.
|Quarterly Reports (5-10 lines)
||Surveillance is in progress
in 9 CRS from September 2012