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 Field
Epidemiology Training Programme (FETP)
Leprosy
vaccine trial
Clinical
trial for traditional remedies
Diabetes
mellitus
Chronic
hepatitis C
Acute
hepatitis C
Epidemiology
of sexually transmitted infections in a
rural community adjacent to truck stops
Establishment
and validation of Multiplex PCR assays for
the etiologic diagnosis of genital ulcer
diseases and genital discharge
diseases
Sexually
transmitted infections and risk behaviour
in couples requiring STD care and development
of prevention intervention for STD patients
Epidemiological
profile of Acute Lower Respiratory Infection
(ALRI) among pre-school children in rural
South India
Standardization
of PCR-based technique for detection of
viruses and bacteria commonly causing
acute lower respiratory tract infections
in children
Study
on Cardiovascular disease risk factors among
industrial population in Chennai
Estimation
of levels, patterns and trends of mortality
in India using decennial census 1951-2001
Uniform
Multi-Drug Therapy (MDT) regimen for all
leprosy patients
Prevalence
of neurological lesions in MB patients,
5 years or more after completion of WHO
MB MDT regimen
Intervention
study to reduce Infant Mortality Rate in
a selected district of Tamil Nadu
Cochrane
review on BCG vaccination for preventing
leprosy
Lot
Quality Assurance Sampling (LQAS) for monitoring
immunization coverage in Tamil Nadu
Formative
research leading to the development of an
intervention to reduce the risk of sexual
transmission of HIV and
Sexually Transmitted Infections (STIs) among
Injection Drug Users (IDUs)
and their sexual partner in Chennai
Nutritional
status and HIV infection among IDUs in Chennai
- A cross - sectional study
Maternal
transmission of HBV / HCV
Training
activities
Six
scholars were selected for the second cohort
( 2002 - 2003 ) of the 2-year Field Epidemiology
Training Programme ( FETP ) leading to Master
of Applied Epidemiology ( MAE ) degree.
Intensive training on basic concepts of
epidemiology and biostatistics was given
to them during their first
contact session of 3 months from January
2002.
Six
of the eight scholars of the first cohort
are continuing the course. All of them have
completed their field
projects successfully. They had developed
their major project proposals in consultation
with the FETP-Consultants
and Faculty members during their 3rd contact
session in March/April 2002.
Organized
five 10-day WHO South East Asia Regional
Workshops on 'Surveillance, Epidemic Preparedness
and Response".
Conducted
a 5-day Basic Course in Statistics for Medical
Doctors and a 2-week Training Programme
on Controlled Clinical Trials with special
reference to Good Clinical Practice guidelines.
Outbreak
investigations
Investigation
of an outbreak of leptospirosis among residents
of nurses hostel in Chennai city was
carried out. Use of contaminated water from
a sump was identified as the most likely
source of infection.
An
awareness programme on leptospirosis and
dengue was carried out in Thodupuzha Taluk,
Idukki Dist., Kerala following
an outbreak of febrile illness among agricultural
workers and rubber plantation
employees.
A
dengue fever outbreak in Chennai city and
a food poisoning episode in a school hostel
in Tiruchi were investigated.
Surveillance
Analysis of information on deaths collected
from vital events registers of 2 Health
Unit Districts in Tamil Nadu for the years
1995 - 1999 revealed elevation of mortality
rates among males aged 40 - 59 years. This
finding was consistent both at District
and PHC level and also for each year.
Leprosy
related work
Third
resurvey of the Leprosy Vaccine Trial (LVT)
population has been completed.
Geographical
Information System (GIS) was utilized to
study the spatial auto correlation of leprosy prevalence
in the LVT trial area.
Follow-up
of 1,595 Pauci-Bacillary (PB) cases with
2-5 lesions and 1,263 single lesion cases
recruited for the multi-centric
clinical trial of single dose of Rifampicin,
Ofloxacin and Minocycline (ROM)
for PB leprosy cases is underway.
Modification
in the simulation model for leprosy transmission
and control to make it user-friendly for
programme managers is nearing completion.
HIV
/ AIDS studies
A study to assess gender differences in
HIV risk behaviour among 206 STD clinic
attendees has revealed a strong need for
tailoring HIV preventive intervention for
each gender separately. Data collection
from 511 STD clinic attendees of the Government
General Hospital, Chennai was completed
to study their attitude towards HIV testing
Traditional
Medicine Research
Involvement in co-ordination of Council's
Traditional Medicine Research programme
continued this year also. Trial of Vijayasar
( Pterocarpus marsupium ) among specific
groups of Type 2 diabetes mellitus patients
has been completed. The protocol for extending
this trial with a higher dose (upto 6g)
of Vijayasar among those who could not achieve
plasma glucose control with 4g is being
finalized.
Meta-analysis
A meta-analysis was carried out to estimate
cure, relapse and success rates of short-course
chemotherapy in the treatment of pulmonary
tuberculosis.
Collaborative
work
Activities on the following collaborative
works are underway
ICMR-sponsored
clinical trial for Chronic Hepatitis-C
ICMR
study to estimate the Cause of Death by
Verbal Autopsy
ICMR-funded
study on maternal transmission of HBV &
HCV.
Study
– Tracking Financial Flows of Health
Research & Development in India.
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